Propylamine → 2-(3-Nitro-6-propylaminophenyl)-5-bromo-7-fluorobenzoxazole
Reaktionsgleichung
[N+:1]([C:4]1[CH:5]=[C:6]([C:11]2[O:12][C:13]3[C:19]([F:20])=[CH:18][C:17]([Br:21])=[CH:16][C:14]=3[N:15]=2)[C:7](F)=[CH:8][CH:9]=1)([O-:3])=[O:2].[CH2:22]([NH2:25])[CH2:23][CH3:24]>>[N+:1]([C:4]1[CH:5]=[C:6]([C:11]2[O:12][C:13]3[C:19]([F:20])=[CH:18][C:17]([Br:21])=[CH:16][C:14]=3[N:15]=2)[C:7]([NH:25][CH2:22][CH2:23][CH3:24])=[CH:8][CH:9]=1)([O-:3])=[O:2]Komponenten
3
Versuchsvorschrift
Prepared by the method of Example 54a), from 2-(3-nitro-6-fluorophenyl)-5-bromo-7-fluorobenzoxazole (284 mg, 0.8 mmol) and propylamine (328 μL, 4.0 mmol) the subtitle compound was obtained. The product was used directly in the next step without purification.
Quellen und Nachweise
- ORD-Eintrag
- ord-d7693d5218ef4f248992f33397a27bfe
- Quelldatensatz
- uspto-grants-2006_11