Benzo(B)Thiophene-2-Boronic Acid → HCID 21884571, Verbindung
Reaktionsgleichung
[N+:1]([C:4]1[CH:5]=[C:6]([C:12]2[O:13][C:14]3[CH:20]=[CH:19][C:18](Br)=[CH:17][C:15]=3[N:16]=2)[C:7]([O:10][CH3:11])=[CH:8][CH:9]=1)([O-:3])=[O:2].[S:22]1[C:26]2[CH:27]=[CH:28][CH:29]=[CH:30][C:25]=2[CH:24]=[C:23]1B(O)O>>[N+:1]([C:4]1[CH:5]=[C:6]([C:12]2[O:13][C:14]3[CH:20]=[CH:19][C:18]([C:23]4[S:22][C:26]5[CH:27]=[CH:28][CH:29]=[CH:30][C:25]=5[CH:24]=4)=[CH:17][C:15]=3[N:16]=2)[C:7]([O:10][CH3:11])=[CH:8][CH:9]=1)([O-:3])=[O:2]Komponenten
3
Versuchsvorschrift
Prepared by the method of Example 15d), from 2-(3-nitro-6-methoxyphenyl)-5-bromobenzoxazole (400 mg, 1.14 mmol) and benzothiophene-2-boronic acid (306 mg, 1.71 mmol) the subtitle compound was obtained (569 mg, 123%). The product was used directly in the next step without purification.
Quellen und Nachweise
- ORD-Eintrag
- ord-255b0c8539eb4db08b4c5b9cd3843eae
- Quelldatensatz
- uspto-grants-2006_11
- Patentnummer
- US07138425B2