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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 722968Erstellt: 25. Oktober 2026

8-[3-(4-piperidinyl)propanoyl]1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one → 8-(3-{1-[2-(2-Chlorophenyl)ethyl]-4-piperidinyl}propanoyl)-1,2,5,6-tetrahydro-4H-pyrrolo[3,2, 1-ij]quinolin-4-one hydrochloride

https://huagongshe.com/reaction/722968

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt8-[3-(4-piperidinyl)propanoyl]1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinolin-4-oneHCID 9966544—
Edukt2-(2-Chlorophenyl)ethyl methanesulfonateHCID 21888087—
Produkt8-(3-{1-[2-(2-Chlorophenyl)ethyl]-4-piperidinyl}propanoyl)-1,2,5,6-tetrahydro-4H-pyrrolo[3,2, 1-ij]quinolin-4-one hydrochlorideHCID 21887350—

Reaktionsschritte

Using 8-[3-(4-piperidinyl)propanoyl]-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one (600 mg and 2-(2-chlorophenyl)ethyl methanesulfonate (475 mg) according to the same method as that of Example 81, the title compound (303 mg) was obtained as colorless crystals having a melting point of 207 to 210° C.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07138533B2
Quelldatensatzuspto-grants-2006_11
ORD IDord-21e6138f4a8b44fda5867152cb141e95
Quellennotizuspto-grants-2006_11