Methyl 2,5-Dichloronicotinate → HCID 67958251, Verbindung
Reaktionsgleichung
Cl[C:2]1[N:11]=[CH:10][C:9]([Cl:12])=[CH:8][C:3]=1[C:4]([O:6][CH3:7])=[O:5].[F:13][C:14]1[CH:19]=[CH:18][C:17]([NH:20][CH:21]2[CH2:24][NH:23][CH2:22]2)=[CH:16][CH:15]=1>>[Cl:12][C:9]1[CH:10]=[N:11][C:2]([N:23]2[CH2:24][CH:21]([NH:20][C:17]3[CH:16]=[CH:15][C:14]([F:13])=[CH:19][CH:18]=3)[CH2:22]2)=[C:3]([CH:8]=1)[C:4]([O:6][CH3:7])=[O:5]Komponenten
3
Versuchsvorschrift
The title compound (D84) (79 mg) was prepared according to the experimental procedure described in Description 62 starting from Methyl 2,5-dichloronicotinate (62.06 mg, 0.3 mmol) and N-(4-fluorophenyl)azetidin-3-amine (D54) (60 mg, 0.361 mmol).
Quellen und Nachweise
- ORD-Eintrag
- ord-00d6f91e2a6140f998827f8ce73772d8
- Quelldatensatz
- uspto-grants-2014_09
- Patentnummer