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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 724831Erstellt: 25. Oktober 2026

p-Toluenesulfonic acid → 3-Ethoxycarbonyl-3-(4-nitrophenyl)propionic acid

https://huagongshe.com/reaction/724831

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Eduktp-Toluenesulfonic acidHCID 6101—
EduktTrifluoroacetic acidHCID 6422—
Edukt(4-Nitrophenyl)acetateHCID 6931101—
LösungsmittelBenzeneHCID 241—
Produkt3-Ethoxycarbonyl-3-(4-nitrophenyl)propionic acidHCID 11807640—

Reaktionsschritte

Following a similar procedure to that described in reference example 7b, but starting fromethyl 4-nitrophenylacetate instead of ethyl diphenylacetate, and hydrolizing then the tert-butyl ester using p-toluenesulfonic acid in benzene at reflux instead of using trifluoroacetic acid, the title compound was obtained.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS05705504
Quelldatensatzuspto-grants-1998_01
ORD IDord-c2c552ccf12b44bfa6feed885d81df99
Quellennotizuspto-grants-1998_01