HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Methyl 4-(1-aminocyclopropyl)benzoate hydrochloride → Methyl 4-(1-(5-chloro-2-(3-phenoxyazetidin-1-yl)nicotinamido)cyclopropyl)benzoate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Methyl 4-(1-aminocyclopropyl)benzoate hydrochloride | HCID 66824369 | — |
| Edukt | 5-Chloro-2-(3-phenoxyazetidin-1-yl)nicotinic acid | HCID 67958240 | — |
| Produkt | Methyl 4-(1-(5-chloro-2-(3-phenoxyazetidin-1-yl)nicotinamido)cyclopropyl)benzoate | HCID 67958677 | 117,7% |
Reaktionsschritte
The title compound (D145) (225 mg) was prepared according to the experimental procedure described in Description 142 starting from 5-chloro-2-(3-phenoxyazetidin-1-yl)nicotinic acid (D101) (140 mg, 0.46 mmol) and methyl 4-(1-aminocyclopropyl)benzoate hydrochloride (D7) (104 mg, 0.40 mmol).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08828987B2 |
| Quelldatensatz | uspto-grants-2014_09 |
| ORD ID | ord-29f935d192b940d8abb4326f426f22f1 |
| Quellennotiz | uspto-grants-2014_09 |