(R)-tert-butyl 3-(3-fluorophenoxy)pyrrolidine-1-carboxylate → (R)-methyl 4-(1-(5-chloro-2-(3-(3-fluorophenoxy)pyrrolidin-1-yl)nicotinamido)cyclopropyl)benzoate

Beteiligte Stoffe

Reaktionsschritte

The title compound (D205) (96 mg) was prepared according to the experimental procedure described in Description 160 starting from (R)-tert-butyl 3-(3-fluorophenoxy)pyrrolidine-1-carboxylate (D47) (100 mg, 0.355 mmol) and reacting in the second step with methyl 4-(1-(2,5-dichloronicotinamido)cyclopropyl)benzoate (D97) (D021/056/3) (65 mg, 0.177 mmol).

Herkunft & Nachweise