Reaktionsgleichung
[CH3:1][C:2]1([CH3:18])[CH2:11][CH2:10][C:9]([CH3:13])([CH3:12])[C:8]2[CH:7]=[C:6]([CH2:14][C:15]([OH:17])=[O:16])[CH:5]=[CH:4][C:3]1=2.S(=O)(=O)(O)O.[CH3:24]O>>[CH3:1][C:2]1([CH3:18])[CH2:11][CH2:10][C:9]([CH3:12])([CH3:13])[C:8]2[CH:7]=[C:6]([CH2:14][C:15]([O:17][CH3:24])=[O:16])[CH:5]=[CH:4][C:3]1=2Komponenten
4
Versuchsvorschrift
15 g (0.06 mol) of 5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthylacetic acid, 150 ml of methanol and 1.6 ml of concentrated sulfuric acid were introduced into a round-bottomed flask. The mixture was heated at reflux for 4 hours, the reaction medium evaporated, taken up in water, and extracted with ethyl acetate. The organic phase was decanted off and dried over magnesium sulfate. 15.9 g (99%) of the expected ester of melting point 83°-85° C. were recovered.
Aufarbeitung
- temperatureThe mixture was heated
- temperatureat reflux for 4 hours
- customthe reaction medium evaporated
- extractionextracted with ethyl acetate
- customThe organic phase was decanted off
- dry with materialdried over magnesium sulfate
- custom15.9 g (99%) of the expected ester of melting point 83°-85° C. were recovered
Quellen und Nachweise
- ORD-Eintrag
- ord-046ba181169c4cb0a27011df122e9299
- Quelldatensatz
- uspto-grants-1998_01
- Patentnummer
- US05709867
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