Hydrochloric Acid → 4-[1-(1-Imidazolyl)-butyl]-benzoic acid, hydrochloride

HRID 727843Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 727843
[N:1]1([CH:6]([C:10]2[CH:18]=[CH:17][C:13]([C:14]([OH:16])=[O:15])=[CH:12][CH:11]=2)[CH2:7][CH2:8][CH3:9])[CH:5]=[CH:4][N:3]=[CH:2]1.[ClH:19]>C(O)C>[ClH:19].[N:1]1([CH:6]([C:10]2[CH:18]=[CH:17][C:13]([C:14]([OH:16])=[O:15])=[CH:12][CH:11]=2)[CH2:7][CH2:8][CH3:9])[CH:5]=[CH:4][N:3]=[CH:2]1

Komponenten

4

Edukt 2

HCID 313Hydrochloric AcidHCID 145143684-[1-(1-Imidazolyl)-butyl]-benzoic acid

Produkt 1

HCID 145143694-[1-(1-Imidazolyl)-butyl]-benzoic acid, hydrochloride

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

1.0 g of 4-[1-(1-imidazolyl)-butyl]-benzoic acid is dissolved in 20 ml of ethanol and mixed with 10 ml of concentrated hydrochloric acid. The reaction mixture is precipitated into 100 ml of water and the precipitate is suctioned off. After recrystallization from ethanol, 0.95 g of 4-[1-(1-imidazolyl)-butyl]-benzoic acid, hydrochloride with a melting point of 38° C. is obtained.

Aufarbeitung

  1. customThe reaction mixture is precipitated into 100 ml of water
  2. customAfter recrystallization from ethanol, 0.95 g of 4-[1-(1-imidazolyl)-butyl]-benzoic acid, hydrochloride with a melting point of 38° C.
  3. customis obtained

Quellen und Nachweise

ORD-Eintrag
ord-fc283fd46dc345c19663bdc84467f22e
Quelldatensatz
uspto-grants-1991_09
Patentnummer
US05045558

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