Phosphoric Acid → HCID 67689897, Verbindung
Reaktionsgleichung
[O:1]1[CH:3]([CH2:4][O:5][C:6]2[CH:11]=[CH:10][C:9]([CH2:12][CH2:13][O:14][CH3:15])=[CH:8][CH:7]=2)[CH2:2]1.Cl.[CH3:17][S:18]([NH:21][C:22]1[CH:35]=[CH:34][C:25]([C:26]([N:28]2[CH2:33][CH2:32][NH:31][CH2:30][CH2:29]2)=[O:27])=[CH:24][CH:23]=1)(=[O:20])=[O:19].[OH-].[Na+].[P:38](=[O:42])([OH:41])([OH:40])[OH:39]>>[P:38](=[O:39])([OH:42])([OH:41])[OH:40].[OH:1][CH:3]([CH2:4][O:5][C:6]1[CH:11]=[CH:10][C:9]([CH2:12][CH2:13][O:14][CH3:15])=[CH:8][CH:7]=1)[CH2:2][N:31]1[CH2:32][CH2:33][N:28]([C:26](=[O:27])[C:25]2[CH:34]=[CH:35][C:22]([NH:21][S:18]([CH3:17])(=[O:20])=[O:19])=[CH:23][CH:24]=2)[CH2:29][CH2:30]1Komponenten
5
Versuchsvorschrift
Add 2.64 g (.013 mol) of 1,2-epoxy-3-[4-(2-methoxyethyl)phenoxy]propane to a solution of 3.86 (12 mmol) 1-[4-[(methylsulfonyl)amino]benzoyl]piperazine hydrochloride in 50 mL MeOHand 13 mL 1 N NaOH. Heat the resultant solution at 50° C. for about 24 h. Cool the solution to room temperature and evaporate the solvents. Dissolve the resultant oil in ethanol and acidify with one equivalent of phosphoric acid. Remove the solvents to obtain the title compound.