HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Iodine chloride → 2-Methoxy-5-Methylaniline
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Iodine chloride | HCID 24640 | — |
| Edukt | N-bromobutanimide | HCID 67184 | — |
| Edukt | 7-Iodo-N-(2-methoxy-5-methylphenyl)-1-benzofuran-5-sulfonamide | HCID 66892506 | — |
| Produkt | 2-Methoxy-5-Methylaniline | HCID 8445 | — |
Reaktionsschritte
7-iodo-N-(2-methoxy-5-methylphenyl)-1-benzofuran-5-sulfonamide is produced starting from 2,3-dihydrobensofuran. Treatment with chlorosulfonic acid gives the corresponding sulfonyl chloride, which is iodinated using iodine monochloride. Aromatization is done using NBS, resulting in 7-iodo-N-(2-methoxy-5-methylphenyl)-1-benzofuran-5-sulfonamide after treatment with cresidine.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07582767B2 |
| Quelldatensatz | uspto-grants-2009_09 |
| ORD ID | ord-976addb137994549b4eb022567162e52 |
| Quellennotiz | uspto-grants-2009_09 |