Diisopropylethylamine → 6-Chloro-2-[4-(3-chloropyridin-2-yl)piperazin-1-yl]-1H-benzoimidazole

Beteiligte Stoffe

Reaktionsschritte

The 2,5-dichloro-1H-benzoimidazole (0.244 g, 1.3 mmol, Example 20b), 1(3-chloropyridin-2-yl)piperazine hydrochloride (0.4 g, 1.7 mmol, Example 3b) and N,N-diisopropylethylamine (0.59 mL, 3.4 mmol, Aldrich) were reacted under the conditions of Example 3c to give the title compound as a white solid. M.p. 214-215° C. MS (ESI, pos. ion) m/z: 348 (M+1).

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