Diisopropylethylamine → 6-Bromo-2-[4-(3-chloropyridin-2-yl)piperazin-1-yl]-1H-benzoimidazole

Beteiligte Stoffe

Reaktionsschritte

The 5-bromo-2-chloro-1H-benzoimidazole (0.115 g, 0.5 mmol, Example 23b), 1-(3-chloropyridin-2-yl)piperazine (0.198 g, 1 mmo, Example 3b) and N,N-diisopropylethylamine (0.35 mL, 2 mmol, Aldrich) were reacted under the conditions of Example 3c to give the title compound as a white solid. M.p. 207-208° C. MS (ESI; pos.,ion) m/z: 394 (M+1).

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