Thionyl Chloride → 5-Bromo-1-chloro-2,3-dihydro-1H-indene

HRID 731181Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 731181
[Br:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[CH:7](O)[CH2:6][CH2:5]2.S(Cl)([Cl:14])=O>C(Cl)Cl>[Br:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[CH:7]([Cl:14])[CH2:6][CH2:5]2

Komponenten

4

Edukt 2

HCID 24386Thionyl ChlorideHCID 134862995-bromo-2,3-dihydro-1H-inden-1-ol

Produkt 1

HCID 223495155-Bromo-1-chloro-2,3-dihydro-1H-indene

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel

Versuchsvorschrift

A mixture of 47.2 (11.1 mmol) and thionyl chloride (44 mmol) in DCM (20 mL) was stirred at room temperature overnight. After evaporation of solvent, 47.3 was obtained and it was used without further purification.

Aufarbeitung

  1. customAfter evaporation of solvent
  2. custom47.3 was obtained
  3. customit was used without further purification

Quellen und Nachweise

ORD-Eintrag
ord-5026e2f771874f2087328fd253aa1a6f
Quelldatensatz
uspto-grants-2009_09
Patentnummer
US07582803B2

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