HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Ammonia → Ammonia
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Ammonia | HCID 222 | — |
| Edukt | Sulfuryl chloride | HCID 24648 | — |
| Edukt | Phosphorus oxychloride | HCID 24813 | — |
| Edukt | Sulfolane | HCID 31347 | — |
| Edukt | Benzenesulfonic acid, 2-amino-5-nitro- | HCID 66786 | — |
| Edukt | Sodium | HCID 5360545 | — |
| Lösungsmittel | Methanol | HCID 887 | — |
| Produkt | Ammonia | HCID 222 | — |
| Produkt | 2-Amino-5-nitrobenzenesulfonamide | HCID 15358386 | — |
Reaktionsschritte
The commercially available sodium salt of 2-amino-5-nitro-benzenesulfonic acid can be converted to the corresponding sulfonyl chloride with phosphoryl chloride in the presence of a suitable co-solvent, such as sulfolane. Treatment with ammonia, e.g., ammonia solution in methanol or ammonia gas, affords the desired 2-amino-5-nitro-benzenesulfonamide intermediate.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07582626B2 |
| Quelldatensatz | uspto-grants-2009_09 |
| ORD ID | ord-f167e916d5f747d49eea0772ec8a6052 |
| Quellennotiz | uspto-grants-2009_09 |