N-(4-phenylcyclohexyl)cycloheptanamine → 2-{2-[3-Cycloheptyl-3-(4-phenyl-cyclohexyl)-ureido]-thiazol-5-ylsulfanyl}-2-methyl-propionic acid
Reaktionsgleichung
C1(N([C@H]2CC[C@H](CC)CC2)C(=O)NC2SC(SC[C:16](O)=[O:17])=CN=2)CCCC1.[CH:28]1([NH:35][CH:36]2[CH2:41][CH2:40][CH:39]([C:42]3[CH:47]=[CH:46][CH:45]=[CH:44][CH:43]=3)[CH2:38][CH2:37]2)[CH2:34][CH2:33][CH2:32][CH2:31][CH2:30][CH2:29]1.C([O:50][C:51](=[O:62])[C:52]([S:55][C:56]1[S:60][C:59]([NH2:61])=[N:58][CH:57]=1)([CH3:54])[CH3:53])C>>[CH:28]1([N:35]([CH:36]2[CH2:41][CH2:40][CH:39]([C:42]3[CH:43]=[CH:44][CH:45]=[CH:46][CH:47]=3)[CH2:38][CH2:37]2)[C:16](=[O:17])[NH:61][C:59]2[S:60][C:56]([S:55][C:52]([CH3:54])([CH3:53])[C:51]([OH:50])=[O:62])=[CH:57][N:58]=2)[CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34]1Komponenten
4
Versuchsvorschrift
Prepared in a similar manner to {2-[3-cyclopentyl-3-(trans-4-ethyl-cyclohexyl)-ureido]-thiazol-5-ylsulfanyl}-acetic acid (via cycloheptyl-(4-phenyl-cyclohexyl)-amine and 2-(2-amino-thiazol-5-ylsulfanyl)-2-methyl-propionic acid ethyl ester.