HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Cyclobutanecarboxylic acid → Cyclobutanecarboxylic acid [2-(5-methyl-3-phenyl-isoxazol-4-yl)-imidazo[1,2-a]pyridin-7-yl]-amide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Cyclobutanecarboxylic acid | HCID 19494 | — |
| Edukt | 2-(5-Methyl-3-phenyl-isoxazol-4-yl)-imidazo[1,2-a]pyridin-7-ylamine | HCID 24738830 | — |
| Produkt | Cyclobutanecarboxylic acid [2-(5-methyl-3-phenyl-isoxazol-4-yl)-imidazo[1,2-a]pyridin-7-yl]-amide | HCID 24738832 | 15% |
Reaktionsschritte
As described for Example 47, 2-(5-methyl-3-phenyl-isoxazol-4-yl)-imidazo[1,2-a]pyridin-7-ylamine (92 mg, 0.32 mmol) was converted, using cyclobutanecarboxylic acid instead of 3-pyridylacetic acid, to the title compound (16.4 mg, 15%) which was obtained as an off-white solid. MS: m/e=373.3 [M+H]+.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07585874B2 |
| Quelldatensatz | uspto-grants-2009_09 |
| ORD ID | ord-7cfd21ebe3b44bf6a625c80a01e64861 |
| Quellennotiz | uspto-grants-2009_09 |