1,1'-Biphenyl-3-ylmethylamine hydrobromide → N-(1,1'-biphenyl-3-ylmethyl)-N-[4-(3-octyl-1,2,4-oxadiazol-5-yl)benzyl]amine

HRID 735965Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 735965
[CH2:1]([C:9]1[N:13]=[C:12]([C:14]2[CH:21]=[CH:20][C:17]([CH:18]=O)=[CH:16][CH:15]=2)[O:11][N:10]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8].Br.[C:23]1([C:31]2[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=2)[CH:28]=[CH:27][CH:26]=[C:25]([CH2:29][NH2:30])[CH:24]=1>>[C:23]1([C:31]2[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=2)[CH:28]=[CH:27][CH:26]=[C:25]([CH2:29][NH:30][CH2:18][C:17]2[CH:20]=[CH:21][C:14]([C:12]3[O:11][N:10]=[C:9]([CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8])[N:13]=3)=[CH:15][CH:16]=2)[CH:24]=1

Komponenten

3

Edukt 2

HCID 671880441,1'-Biphenyl-3-ylmethylamine hydrobromideHCID 865985324-(3-Octyl-1,2,4-oxadiazol-5-yl)benzaldehyde

Produkt 1

HCID 67186930N-(1,1'-biphenyl-3-ylmethyl)-N-[4-(3-octyl-1,2,4-oxadiazol-5-yl)benzyl]amine

Versuchsvorschrift

The same procedure as employed in the preparation of Example 357 (step a) but using 4-(3-octyl-1,2,4-oxadiazol-5-yl)benzaldehyde and 1,1′-biphenyl-3-ylmethylamine hydrobromide gave the title compound as an oil. M+(LC/MS(ESI)): 454.6 HPLC (Condition A), Rt: 4.52 min (HPLC purity: 81%).

Aufarbeitung

  1. customThe same procedure as employed in the preparation of Example 357 (step a) but

Quellen und Nachweise

ORD-Eintrag
ord-c580ce8daf2b4872a574091b813b26d5
Quelldatensatz
uspto-grants-2009_09
Patentnummer
US07592477B2

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