HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-cyclopropyl-1H-imidazole → [5-(2-Cyclopropyl-imidazol-1-yl)-2-morpholin-4-yl-phenyl]-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-methanone
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-cyclopropyl-1H-imidazole | HCID 17942383 | — |
| Edukt | (5-Bromo-2-morpholin-4-yl-phenyl)-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-methanone | HCID 59793730 | — |
| Produkt | [5-(2-Cyclopropyl-imidazol-1-yl)-2-morpholin-4-yl-phenyl]-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-methanone | HCID 68841917 | 16% |
Reaktionsschritte
The title compound was prepared according to the procedure described for example 199 from (5-Bromo-2-morpholin-4-yl-phenyl)-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-methanone (compound CR) and 2-Cyclopropyl-1H-imidazole (CAS: 89532-38-7) (16% yield, white solid, MS (m/e): 526.3 (M+H, 100%)
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07595314B2 |
| Quelldatensatz | uspto-grants-2009_09 |
| ORD ID | ord-079f3da0462b4aa58a68ba1f2444ec9f |
| Quellennotiz | uspto-grants-2009_09 |