Cyclopropanemethanamine → [2-(Cyclopropylmethyl-amino)-5-methanesulfonyl-phenyl]-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-methanone

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	Cyclopropanemethanamine	HCID 75646	—
Edukt	(2-Iodo-5-methanesulfonyl-phenyl)-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-methanone	HCID 59793691	—
Produkt	[2-(Cyclopropylmethyl-amino)-5-methanesulfonyl-phenyl]-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-methanone	HCID 68839612	40%

Reaktionsschritte

The title compound was prepared according to the procedure described for example 301 from (2-Iodo-5-methanesulfonyl-phenyl)-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-methanone (compound CK) and Cyclopropanemethylamine (40% yield, white foam, MS (m/e): 482.5 (M+H, 100%)

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US07595314B2
Quelldatensatz	uspto-grants-2009_09
ORD ID	ord-8bbbab9123c34ae59080b5cdf7ff712c
Quellennotiz	uspto-grants-2009_09