HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Glycine methyl ester hydrochloride → (4-{1-Ethyl-1-[4-(2-ethyl-2-hydroxy-butoxy)-3-methyl-phenyl]-propyl}-2-methyl-benzoylamino)-acetic acid methyl ester
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Glycine methyl ester hydrochloride | HCID 122755 | — |
| Edukt | 4-{1-Ethyl-1-[4-(2-ethyl-2-hydroxy-butoxy)-3-methyl-phenyl]-propyl}-2-methyl-benzoic acid | HCID 57849335 | — |
| Produkt | (4-{1-Ethyl-1-[4-(2-ethyl-2-hydroxy-butoxy)-3-methyl-phenyl]-propyl}-2-methyl-benzoylamino)-acetic acid methyl ester | HCID 57849322 | 96,1% |
Reaktionsschritte
Using a procedure analogous to Example 1J, 4-{1-ethyl-1-[4-(2-ethyl-2-hydroxy-butoxy)-3-methyl-phenyl]-propyl}-2-methyl-benzoic acid (0.64 g, 1.55 mmol) and glycine methyl ester hydrochloride (195 mg, 1.55 mmol) gives the title compound (0.72 g, 1.49 mmol, 96%). %).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07595345B2 |
| Quelldatensatz | uspto-grants-2009_09 |
| ORD ID | ord-2cbf12a32a514f7680ea3c9b5331f2e9 |
| Quellennotiz | uspto-grants-2009_09 |