1,2-Benzisothiazol-3(2H)-one → 3-Oxo-3H-benzo[d]isothiazole-2-carboxylic acid dodecylamide

Beteiligte Stoffe

Reaktionsschritte

Following the synthetic procedure of 6a as described in Example 1, compound 6g (78% yield) was synthesized from benzo[d]isothiazol-3-one and dodecyl isocyanate as a white solid. mp 66-67° C.; IR(CHCl3) 3279, 1709, 1660, 1536 cm−1; 1H-NMR (CDCl3) δ0.87 (t, J=6.8 Hz, 3H), 1.20-1.39 (m, 18H), 1.59-1.66 (m, 2H), 3.40-3.46 (m, 2H), 7.42 (t, J=7.6 Hz, 1H), 7.57 (d, J=7.6 Hz, 1H), 7.69 (t, J=7.6 Hz, 1H), 8.01 (d, J=7.6 Hz, 1H), 8.87 (br s, 1H); ESIMS m/e 363 (M++1).

Herkunft & Nachweise