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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 737093Erstellt: 23. Oktober 2026

Acetonitrile → 1-(4-Bromo-benzyl)-3-phenyl-piperidine

https://huagongshe.com/de/reaction/737093

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktAcetonitrileHCID 6342—
EduktPotassium CarbonateHCID 11430—
Edukt4-Bromobenzyl bromideHCID 68527—
Edukt2-PhenylpiperidineHCID 103020—
Produkt1-(4-Bromo-benzyl)-3-phenyl-piperidineHCID 5784957154%

Reaktionsschritte

5.632 g of 4-Bromobenzyl bromide and 2.422 g of 2-Phenylpiperidine (Array) in 50 mL of acetonitrile were stirred at room temperature and 6.229 g of potassium carbonate was added. The reaction was stirred at room temperature overnight. The solution was filtered through Celite and concentrated in vacuo to afford a brown solid. Purification was done by flash chromatography to afford product. Wt:0.908 g, 54% yield.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07595397B2
Quelldatensatzuspto-grants-2009_09
ORD IDord-34fa2b02ab2e469ea65d7e888a05af06
Quellennotizuspto-grants-2009_09