1-Chloro-4-(trifluoromethyl)benzene → 4-methyl-N-(4-(trifluoromethyl)phenyl)aniline

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	1-Chloro-4-(trifluoromethyl)benzene	HCID 7394	—
Edukt	p-Toluidine	HCID 7813	—
Reagenz	Ethyl 5-methylisoxazole-3-carboxylate	HCID 76677	—
Reagenz	2,N'3,N'3,N3,N3,N'5,N'5,N5,N5-nonamethyl-2,4,6-triaza-3lambda5,5lambda5-diphosphaocta-3,5-diene-3,3,5,5-tetramine	HCID 3393106	—
Katalysator	HCID 178439018	HCID 178439018	—
Lösungsmittel	Dimethyl Sulfoxide	HCID 679	—
Produkt	4-methyl-N-(4-(trifluoromethyl)phenyl)aniline	HCID 18712799	22,166%

Reaktionsbedingungen

Temperatur	60 °C

Reaktionsschritte

These solutions were added to a 384- well source plate (80 µL per well). The Mosquito HTS liquid handling robot was used to dose each of these solutions (200 nL each) into a 1536-well plate.

Herkunft & Nachweise

DOI	10.1126/science.aar5169
Quelldatensatz	Ahneman
ORD ID	ord-15078f42d6c545dbae57e7831a14f5dd
Quellennotiz	Ahneman