HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
5-Bromo-6-chloropyridine-3-carboxylic acid → 5-bromo-6-chloro-N-(3-fluoro-4-(trifluoromethoxy)phenyl)nicotinamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 5-Bromo-6-chloropyridine-3-carboxylic acid | HCID 285433 | — |
| Edukt | 3-Fluoro-4-(trifluoromethoxy)aniline | HCID 19436618 | — |
| Produkt | 5-bromo-6-chloro-N-(3-fluoro-4-(trifluoromethoxy)phenyl)nicotinamide | HCID 86702608 | — |
Reaktionsschritte
The title compound was prepared in an analogous fashion to that described in Stage 11.2 using 5-bromo-6-chloro-nicotinic acid and 3-fluoro-4-trifluoromethoxy-aniline to afford an off-white crystalline solid. HPLC (Condition 4) tR=6.43 min, UPLC-MS (Condition 3) tR=1.29 min, m/z=413 [M−H]−.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08829195B2 |
| Quelldatensatz | uspto-grants-2014_09 |
| ORD ID | ord-92b981654a5746b697bc6643f622f25e |
| Quellennotiz | uspto-grants-2014_09 |