HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Leucine, N-carboxy-, N-benzyl ester, L- → N-[N-[(Phenylmethoxy)carbonyl]-L-leucyl]-L-norleucinol
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Leucine, N-carboxy-, N-benzyl ester, L- | HCID 74840 | — |
| Edukt | (2S)-2-Amino-1-hexanol | HCID 5494388 | — |
| Produkt | N-[N-[(Phenylmethoxy)carbonyl]-L-leucyl]-L-norleucinol | HCID 15168139 | 58% |
Reaktionsschritte
N-[(phenylmethoxy)carbonyl]-L-leucine was used instead of 1-[[(phenylmethoxy)carbonyl]amino]cyclohexanecarboxylic acid, and L-norleucinol was used instead of L-valinol in the process according to Reference Example 178 to obtain 421 mg (58%) of the title compound.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08829209B2 |
| Quelldatensatz | uspto-grants-2014_09 |
| ORD ID | ord-ac37e11a459a4ff08d4c2ee4c1c96d22 |
| Quellennotiz | uspto-grants-2014_09 |