Acetic acid, 2-oxo-, methyl ester → methyl (2E)-2-[(2-chlorophenyl)hydrazinylidene]acetate
Reaktionsgleichung
[C:1]([O:5][CH3:6])(=[O:4])[CH:2]=O.Cl.[Cl:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[NH:15][NH2:16]>CO>[Cl:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[NH:15]/[N:16]=[CH:2]/[C:1]([O:5][CH3:6])=[O:4]Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
To a solution of methyl glyoxylate (6.8 g, 77 mmol) in methanol (150 mL) was added 2-chlorophenylhydrazine hydrochloride (12.5 g, 77 mmol) and the mixture was heated at reflux overnight, cooled and concentrated. The residue was re-dissolved in toluene and concentrated to give the title compound of Step A.
Aufarbeitung
- temperaturethe mixture was heated
- temperatureat reflux overnight
- temperaturecooled
- concentrationconcentrated
- dissolutionThe residue was re-dissolved in toluene
- concentrationconcentrated
Quellen und Nachweise
- ORD-Eintrag
- ord-a1a53def4c664a96999097c0e8311779
- Quelldatensatz
- uspto-grants-2006_08
- Patentnummer
- US07087598B2
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