2-Chloropropyldimethylamine → 1-(2-bromobenzyl)-2-(3-methylphenyl)-6-[1-methyl-2-(N, N-dimethylamino)ethoxy]benzimidazole
Reaktionsgleichung
[Br:1][C:2]1[CH:25]=[CH:24][CH:23]=[CH:22][C:3]=1[CH2:4][N:5]1[C:9]2[CH:10]=[C:11]([OH:14])[CH:12]=[CH:13][C:8]=2[N:7]=[C:6]1[C:15]1[CH:20]=[CH:19][CH:18]=[C:17]([CH3:21])[CH:16]=1.[CH3:26][CH:27](Cl)[CH2:28][N:29]([CH3:31])[CH3:30]>>[Br:1][C:2]1[CH:25]=[CH:24][CH:23]=[CH:22][C:3]=1[CH2:4][N:5]1[C:9]2[CH:10]=[C:11]([O:14][CH:27]([CH3:26])[CH2:28][N:29]([CH3:31])[CH3:30])[CH:12]=[CH:13][C:8]=2[N:7]=[C:6]1[C:15]1[CH:20]=[CH:19][CH:18]=[C:17]([CH3:21])[CH:16]=1Komponenten
3
Versuchsvorschrift
The title compound was prepared essentially as described above except that the compound of Example 126 was reacted with 1-methyl-2-(N,N-dimethylamino)ethyl chloride.
Quellen und Nachweise
- ORD-Eintrag
- ord-478394b7f146421c90c2258f4c3a05b0
- Quelldatensatz
- uspto-grants-1996_09