Triethylamine → 3-(2,3-Dimethylphenyl)-1-ethyl-2-thioxo-imidazolidin-4-one

HRID 742258Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 742258
[CH3:1][C:2]1[C:7]([CH3:8])=[CH:6][CH:5]=[CH:4][C:3]=1[N:9]=[C:10]=[S:11].[CH2:12]([NH:14][CH2:15][C:16](O)=[O:17])[CH3:13].C(N(CC)CC)C>C(Cl)(Cl)Cl>[CH3:1][C:2]1[C:7]([CH3:8])=[CH:6][CH:5]=[CH:4][C:3]=1[N:9]1[C:16](=[O:17])[CH2:15][N:14]([CH2:12][CH3:13])[C:10]1=[S:11]

Komponenten

5

Edukt 3

HCID 8471TriethylamineHCID 1370682,3-DimethylphenylisothiocyanateHCID 316542N-Ethylglycine

Produkt 1

HCID 153894893-(2,3-Dimethylphenyl)-1-ethyl-2-thioxo-imidazolidin-4-oneAusbeute 41,5 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6212ChloroformLösungsmittel

Versuchsvorschrift

The title compound was prepared by the procedure described in Example 16 using 16.3 g of 2,3-dimethylphenyl-isothiocyanate, 18.4 g of N-ethyl glycine, 20.2 g of triethyl amine, and 250 mL of chloroform. Crystallization from ethanol afforded the title compound (10.3 g) as a light pink solid, m.p. 120°-121° C. Anal. Calcd. for. C13H16N2O S: C, 62.87; H, 6.49; N, 11.28. Found: C, 62.72; H,. 6.44; N, 11.47. Mass spectrum (El, M.+) m/z 248.

Aufarbeitung

  1. customThe title compound was prepared by the procedure
  2. customCrystallization from ethanol

Quellen und Nachweise

ORD-Eintrag
ord-aa9ebcac222347fb9dfc2bf8e6b98043
Quelldatensatz
uspto-grants-1996_09
Patentnummer
US05554607

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