2-Chlorobenzaldehyde → 2-Chlorocinnamaldehyde

HRID 743402

Reaktionsgleichung

Reaktionsgleichung von HRID 743402
[Cl:1][C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[CH:4]=O.C1(P(=[CH:29][CH:30]=[O:31])(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1>C(#N)C>[Cl:1][C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[CH:4]=[CH:29][CH:30]=[O:31]

Komponenten

4

Edukt 2

HCID 69962-ChlorobenzaldehydeHCID 75051(Triphenylphosphoranylidene)acetaldehyde

Produkt 1

HCID 30140422-ChlorocinnamaldehydeAusbeute 68,6 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6342AcetonitrileLösungsmittel

Versuchsvorschrift

Following a procedure similar to that described in the first part of Preparation 17, 3.00 g of 2-chlorobenzaldehyde and 7.5 g of (triphenylphosphoranylidene)acetaldehyde were reacted in 100 ml of acetonitrile. The crude product thus obtained was purified by column chromatography through silica gel, using a 4:1 by volume mixture of hexane and ethyl acetate as the eluent, to give 2.44 g (yield 68%) of 3-(2-chlorophenyl)-2-propenal as a solid.

Aufarbeitung

  1. customThe crude product thus obtained
  2. customwas purified by column chromatography through silica gel
  3. additionby volume mixture of hexane and ethyl acetate as the eluent

Quellen und Nachweise

ORD-Eintrag
ord-3ec02909709d487c874bb027c60589aa
Quelldatensatz
uspto-grants-1996_09
Patentnummer
US05556864

Verknüpfte Notizen

Wird geladen…