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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 744423Erstellt: 25. Oktober 2026

Decyl chloroformate → Phthalimide hydrochloride

https://huagongshe.com/reaction/744423

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktDecyl chloroformateHCID 108727—
EduktN-[2-[4-(6-fluoro1H-indazol-3-yl)-1-piperazinyl]ethyl]phthalimideHCID 18467209—
LösungsmittelDiethyl EtherHCID 3283—
ProduktPhthalimide hydrochlorideHCID 22266261—

Reaktionsschritte

A mixture of decanyl chloroformate (2.4 g, 11 mmol), and N-[2-[4-(6-fluoro-1H-indazol-3-yl)-1-piperazinyl]ethyl]phthalimide (3.9 g, 10 mmol) was warmed on the steam bath for 15 minutes. The reaction was allowed to cool to ambient temperature, and then ether was added to the residue. The resulting solid was filtered to afford N-2-[4-(1-decanoxy-6-fluoro-1H-indazol-3-yl)-1-piperazinyl]ethyl]phthalimide hydrochloride.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS05559117
Quelldatensatzuspto-grants-1996_09
ORD IDord-77699d4f57424e13828638df86460020
Quellennotizuspto-grants-1996_09