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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 744639Erstellt: 23. Oktober 2026

Water → cis-3-(3-(3-Hexenyloxy)-1,2,5-thiadiazol-4-yl)pyridine

https://huagongshe.com/de/reaction/744639

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktWaterHCID 962—
EduktSodium hydrideHCID 24758—
Edukt3-HexenolHCID 5281167—
Edukt3-Chloro-4-(pyridin-3-yl)-1,2,5-thiadiazoleHCID 10488164—
LösungsmittelTetrahydrofuranHCID 8028—
Produktcis-3-(3-(3-Hexenyloxy)-1,2,5-thiadiazol-4-yl)pyridineHCID 70144893—

Reaktionsschritte

To a solution of cis-3-hexen-1-ol (900 mg, 9 mmol) and sodium hydride (310 mg, 9 mmol) in dry tetrahydrofuran was added a solution of 3-(4-chloro-1,2,5-thiadiazol-3-yl) pyridine (590 mg, 3 mmol) in dry tetrahydrofuran. The reaction mixture was stirred at room temperature for 1 h. Water was added and the mixture was extracted with ether. The ether phase was dried and evaporated to give the title compound.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS05559138
Quelldatensatzuspto-grants-1996_09
ORD IDord-12110238c5294e78ae8381494095e1e8
Quellennotizuspto-grants-1996_09