Cadaverine → N-(5-Aminopentyl)benzamide

HRID 746502

Reaktionsgleichung

Reaktionsgleichung von HRID 746502
[NH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][NH2:7].[C:8](N)(=[O:15])[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1>>[NH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][NH:7][C:8](=[O:15])[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1

Komponenten

3

Edukt 2

HCID 273CadaverineHCID 2331Benzamide

Produkt 1

HCID 345353N-(5-Aminopentyl)benzamideAusbeute 70,6 %

Versuchsvorschrift

Under an argon atmosphere, 1,5-diaminopentane (25 g, 0.24 mol) and benzamide (9.9 g, 0.081 mol) were combined and heated at reflux overnight. The reaction mixture was concentrated under vacuum to remove the excess diamine. The residue was distilled at about 210° C. at 12 torr (16×102 pascals) to provide 11.8 g of N-(5-aminopentyl)benzamide as a colorless oil.

Aufarbeitung

  1. temperatureheated
  2. temperatureat reflux overnight
  3. concentrationThe reaction mixture was concentrated under vacuum
  4. customto remove the excess diamine
  5. distillationThe residue was distilled at about 210° C. at 12 torr (16×102 pascals)

Quellen und Nachweise

ORD-Eintrag
ord-6b93c46bf3af424ba9e6805efc66fcec
Quelldatensatz
uspto-grants-2008_07
Patentnummer
US07393859B2

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