HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2,3-Dihydroxybutanedioic Acid → (R)-2-(3-(Diisopropylamino)-1-phenylpropyl)-4-methylphenol 2,3-dihydroxysuccinate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2,3-Dihydroxybutanedioic Acid | HCID 875 | — |
| Edukt | Tolterodine | HCID 443879 | — |
| Lösungsmittel | Ethyl Acetate | HCID 8857 | — |
| Produkt | (R)-2-(3-(Diisopropylamino)-1-phenylpropyl)-4-methylphenol 2,3-dihydroxysuccinate | HCID 9847786 | 75,3% |
Reaktionsschritte
Tolterodine free base (2.0 gm) is dissolved in ethyl acetate (25 ml) and tartaric acid (1.2 gm) is added to the solution. Then the contents are maintained for 2 hours at 25° C. to 30° C. and filtered to give 2.2 gm of tolterodine tartrate form II.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07393874B2 |
| Quelldatensatz | uspto-grants-2008_07 |
| ORD ID | ord-f22d16ec5eee45009cd15bc695a90fb6 |
| Quellennotiz | uspto-grants-2008_07 |