5-(Methoxycarbonyl)thiophene-2-carboxylic acid → 5-[1-(3-Bromo-phenyl)-ethylcarbamoyl]-thiophene-2-carboxylic acid methyl ester

HRID 747575

Reaktionsgleichung

Reaktionsgleichung von HRID 747575
[Br:1][C:2]1[CH:3]=[C:4]([CH:8]([NH2:10])[CH3:9])[CH:5]=[CH:6][CH:7]=1.[CH3:11][O:12][C:13]([C:15]1[S:16][C:17]([C:20](O)=[O:21])=[CH:18][CH:19]=1)=[O:14]>>[CH3:11][O:12][C:13]([C:15]1[S:16][C:17]([C:20](=[O:21])[NH:10][CH:8]([C:4]2[CH:5]=[CH:6][CH:7]=[C:2]([Br:1])[CH:3]=2)[CH3:9])=[CH:18][CH:19]=1)=[O:14]

Komponenten

3

Edukt 2

HCID 8183525-(Methoxycarbonyl)thiophene-2-carboxylic acidHCID 167857641-(3-Bromophenyl)ethanamine

Produkt 1

HCID 692928715-[1-(3-Bromo-phenyl)-ethylcarbamoyl]-thiophene-2-carboxylic acid methyl ester

Versuchsvorschrift

The title compound was prepared in an analogous manner to that described in example 1, step 1 from 1-(3-bromo-phenyl)-ethylamine and thiophene-2,5-dicarboxylic acid monomethyl ester.

Quellen und Nachweise

ORD-Eintrag
ord-a4dc2544990342118a0374a736339578
Quelldatensatz
uspto-grants-2008_07
Patentnummer
US07396944B2

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