2-Methoxyphenylboronic acid → 5-{1-[5-(2-Methoxy-phenyl)-thiophen-2-yl]-ethylcarbamoyl}-thiophene-2-carboxylic acid methyl ester

HRID 747578Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 747578
[CH3:1][O:2][C:3]([C:5]1[S:6][C:7]([C:10](=[O:20])[NH:11][CH:12]([C:14]2[S:15][C:16](Br)=[CH:17][CH:18]=2)[CH3:13])=[CH:8][CH:9]=1)=[O:4].[CH3:21][O:22][C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][C:24]=1B(O)O>>[CH3:1][O:2][C:3]([C:5]1[S:6][C:7]([C:10](=[O:20])[NH:11][CH:12]([C:14]2[S:15][C:16]([C:24]3[CH:25]=[CH:26][CH:27]=[CH:28][C:23]=3[O:22][CH3:21])=[CH:17][CH:18]=2)[CH3:13])=[CH:8][CH:9]=1)=[O:4]

Komponenten

3

Edukt 2

HCID 27339582-Methoxyphenylboronic acidHCID 692923405-[1-(5-Bromo-thiophen-2-yl)-ethylcarbamoyl]-thiophene-2-carboxylic acid methyl ester

Produkt 1

HCID 692921925-{1-[5-(2-Methoxy-phenyl)-thiophen-2-yl]-ethylcarbamoyl}-thiophene-2-carboxylic acid methyl ester

Versuchsvorschrift

The title compound was prepared in an analogous manner to that described in example 2, step 3 from 5-[1-(5-bromo-thiophen-2-yl)-ethylcarbamoyl]-thiophene-2-carboxylic acid methyl ester and 2-methoxy-benzene-boronic acid.

Quellen und Nachweise

ORD-Eintrag
ord-5e5de5a515d048e4aa6107aa037f036d
Quelldatensatz
uspto-grants-2008_07
Patentnummer
US07396944B2

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