4-Fluorophenylboronic acid → HCID 11358168, Verbindung
Reaktionsgleichung
C(OC([N:8]1[CH:17]([CH3:18])[CH2:16][C:15]2[C:11](=[C:12](OS(C(F)(F)F)(=O)=O)[N:13]([CH:19]([CH3:21])[CH3:20])[N:14]=2)[CH2:10][CH2:9]1)=O)(C)(C)C.[F:30][C:31]1[CH:36]=[CH:35][C:34](B(O)O)=[CH:33][CH:32]=1.FC1C=CC(C2N(C(C)C)N=C3C=2CC(C)NCC3)=CC=1>>[F:30][C:31]1[CH:36]=[CH:35][C:34]([C:12]2[N:13]([CH:19]([CH3:20])[CH3:21])[N:14]=[C:15]3[C:11]=2[CH2:10][CH2:9][NH:8][CH:17]([CH3:18])[CH2:16]3)=[CH:33][CH:32]=1Komponenten
4
Versuchsvorschrift
The title compound (127 mg) was prepared as in Example 311 using 260 mg of 2-isopropyl-7-methyl-3-trifluoromethanesulfonyloxy-4,5,7,8-tetrahydro-2H-1,2,6-triaza-azulene-6-carboxylic acid tert-butyl ester and 115 of 4-fluorophenylboronic acid. The reaction sequence also yielded 3-(4-fluoro-phenyl)-2-isopropyl-5-methyl-2,4,5,6,7,8-hexahydro-1,2,6-triaza-azulene. MS (ESI): exact mass calculated for C17H22FN3, 287.18; found, m/z 288.5 [M+H]+.