1-Iodo-4-(trifluoromethoxy)benzene → 2-(1H-Indol-6-yl)-N-[3-(4-trifluoromethoxy-phenyl)-prop-2-ynyl]-acetamide

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	1-Iodo-4-(trifluoromethoxy)benzene	HCID 2777294	—
Edukt	2-(1H-Indol-6-yl)-N-prop-2-ynyl-acetamide	HCID 86095505	—
Produkt	2-(1H-Indol-6-yl)-N-[3-(4-trifluoromethoxy-phenyl)-prop-2-ynyl]-acetamide	HCID 68825664	—

Reaktionsschritte

In analogy to the procedure described for example 8 a], 2-(1H-indol-6-yl)-N-prop-2-ynyl-acetamide was reacted with 4-(trifluoromethoxy)-iodobenzene in the presence of PdCl2(Ph3P)2 and cuprous iodide to give the title compound as colorless crystals.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US07405236B2
Quelldatensatz	uspto-grants-2008_07
ORD ID	ord-2d278a71bb944401bfba164c31f4be3d
Quellennotiz	uspto-grants-2008_07