HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Piperidine → 2-(Piperidin-1-yl)-1-phenyl-1H-indole-3-carboxaldehyde
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Piperidine | HCID 8082 | — |
| Edukt | 2-chloro-1-phenyl-1H-indole-3-carbaldehyde | HCID 314793 | — |
| Produkt | 2-(Piperidin-1-yl)-1-phenyl-1H-indole-3-carboxaldehyde | HCID 59754756 | 50% |
Reaktionsschritte
2-Chloro-1-phenyl-1H-indole-3-carboxaldehyde is reacted with piperidine as described in Example 2 to give, after flash chromatography, the title compound (50% yield). NMR (CDCl3) 10.23 (1H, s), 8.29 (1H, d), 7.59 (2H, m), 7.50 (1H, m), 7.40 (2H, d), 7.22 (1H, m), 7.11 (1H, t), 6.98 (1H, d), 3.25 (4H, m), 1.53 (2H, m), 1.42 (4H, m).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07405300B2 |
| Quelldatensatz | uspto-grants-2008_07 |
| ORD ID | ord-cc7061b6b7914ad0af4ebbe8da9612e4 |
| Quellennotiz | uspto-grants-2008_07 |