HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-chloro-1H-indole-3-carbaldehyde → 2-chloro-1-(4-methyl-3-nitrophenyl)-1H-indole-3-carboxaldehyde
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-chloro-1H-indole-3-carbaldehyde | HCID 314791 | — |
| Edukt | 4-Methyl-3-nitrobenzeneboronic acid | HCID 2773515 | — |
| Produkt | 2-chloro-1-(4-methyl-3-nitrophenyl)-1H-indole-3-carboxaldehyde | HCID 86035915 | 35% |
Reaktionsschritte
2-Chloro-1H-indole-3-carboxaldehyde is reacted with 4-methyl-3-nitrophenylboronic acid as described in Step 1 of Example 29 to afford 2-chloro-1-(4-methyl-3-nitrophenyl)-1H-indole-3-carboxaldehyde (35% yield) as a light cream solid. ESI/MS 315 (M+H); 356 [(M+1+CH3CN) adduct]; RT 3.35 min.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07405300B2 |
| Quelldatensatz | uspto-grants-2008_07 |
| ORD ID | ord-1b357d2259294e62b15c333956c0615a |
| Quellennotiz | uspto-grants-2008_07 |