p-Aminoacetophenone → HCID 178466751, Verbindung
Reaktionsgleichung
CC(=O)c1ccc(N)cc1.O=C(O)c1cc(Cl)cc(Cl)n1.CC(C)N=C=NC(C)C.C1=CC2=C(N=C1)N(N=N2)O.CN(C)C=O>>CC(=O)c1ccc(NC(=O)c2cc(Cl)cc(Cl)n2)cc1Komponenten
6
Reaktionsbedingungen
- Temperatur
- 25 °C
Aufarbeitung
- addition150 uL of MeCN/H2O (1:1) mixed solvent was dispensed separately into each plate using the 96-tip head of the Tecan Evo-200.
- addition150 uL of internal standard solution was dispensed separately into each plate using the 96-tip head of the Tecan Evo-200.
- aliquot10 uL aliquot taken from reaction vials, and added to pre-filled wells in the transfer plate.
- addition380 uL MeCN solvent were added to the transfer plate
- aliquot20 uL taken from transfer plate to filter plate 1 for LCMS analysis
- addition180 uL MeCN added to filter plate 1 for LCMS analysis
- aliquot10 uL taken from transfer plate to filter plate 2 for TOF-DESI analysis
- addition190 uL MeCN added to filter plate 2 for TOF-DESI analysis
- customthe 96-well filter plates were centrifuged for 2.5 min at 3000 RPM
Quellen und Nachweise
- ORD-Eintrag
- ord-f3455be54ab74a27a846ef014481037f
- Quelldatensatz
- AIChemEco amide coupling conditions 47k dataset
Notizen zur Reaktion
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