1-Phenylcyclopentanecarboxylic acid → HCID 178441256, Verbindung

HRID 76281

Reaktionsgleichung

Reaktionsgleichung von HRID 76281
[C:1]([N:5]1[CH:9]=[C:8]([CH2:10][CH2:11][CH2:12][CH3:13])[C:7](=[NH:14])[S:6]1)([CH3:4])([CH3:3])[CH3:2].[C:15]1([C:21]2([C:26](O)=[O:27])[CH2:25][CH2:24][CH2:23][CH2:22]2)[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1>>[CH2:10]([C:8]1=[CH:9][N:5]([C:1]([CH3:4])([CH3:3])[CH3:2])[S:6]/[C:7]/1=[N:14]\[C:26]([C:21]1([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[CH2:25][CH2:24][CH2:23][CH2:22]1)=[O:27])[CH2:11][CH2:12][CH3:13]

Komponenten

3

Edukt 2

HCID 661671-Phenylcyclopentanecarboxylic acidHCID 668672282-tert-Butyl-4-butylisothiazol-5(2H)-imine

Produkt 1

HCID 178441256HCID 178441256, Verbindung

Versuchsvorschrift

The product from Example 92B and 1-phenylcyclopentanecarboxylic acid (Aldrich) were processed using the method described in Example 92C to afford the title compound. 1H NMR (DMSO-d6) δ 0.90 (t, J=7.3 Hz, 3H), 1.23-1.35 (m, 2H), 1.54 (s, 9H), 1.54-1.69 (m, 6H), 1.78-1.87 (m, 2H), 2.61-2.66 (m, 2H), 2.86-2.93 (m, 2H), 7.10-7.16 (m, 1H), 7.21-7.26 (m, 2H), 7.31-7.38 (m, 2H), 8.50 (s, 1H). MS (ESI+) m/z 385 (M+H)+. Anal. calcd. for C23H32N2OS: C, 71.83; H, 8.39; N, 7.28. Found: C, 71.58; H, 8.21; N, 7.05.

Quellen und Nachweise

ORD-Eintrag
ord-3bda1999a07f42428ecbacae4d669fb4
Quelldatensatz
uspto-grants-2014_09
Patentnummer
US08835475B2

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