HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Potassium Carbonate → 5-Chloro-2-(2,2,2-trifluoroethoxy)benzoic acid
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Potassium Carbonate | HCID 11430 | — |
| Edukt | Sodium Hydroxide | HCID 14798 | — |
| Edukt | Benzoic acid, 5-chloro-2-hydroxy-, methyl ester | HCID 77684 | — |
| Edukt | 2,2,2-Trifluoroethyl trifluoromethanesulfonate | HCID 80366 | — |
| Produkt | 5-Chloro-2-(2,2,2-trifluoroethoxy)benzoic acid | HCID 43141863 | — |
Reaktionsschritte
Commercially available, methyl 5-chloro-2-hydroxybenzoate (Maybridge), potassium carbonate, 2,2,2-trifluoroethyl trifluoromethanesulfonate (TCI) and sodium hydroxide were processed according to the method of Example 130A to obtain the title compound. MS (ESI+) m/z 253 (M−H)'.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08835475B2 |
| Quelldatensatz | uspto-grants-2014_09 |
| ORD ID | ord-092e969b2e014dc0aba635b79043f1a2 |
| Quellennotiz | uspto-grants-2014_09 |