HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
3-Aminophenol → N2,N4-bis(3-hydroxyphenyl)-5-methyl-2,4-pyrimidinediamine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 3-Aminophenol | HCID 11568 | — |
| Edukt | Pyrimidine, 2,4-dichloro-5-methyl- | HCID 74508 | — |
| Edukt | R-112 | HCID 9904854 | — |
| Produkt | N2,N4-bis(3-hydroxyphenyl)-5-methyl-2,4-pyrimidinediamine | HCID 22061056 | — |
Reaktionsschritte
In a manner analogous to the preparation of N2,N4-bis(3-hydroxyphenyl)-5-fluoro-2,4-pyrimidinediamine, the reaction of 2,4-dichloro-5-methylpyrimidine with 3-hydroxyaniline gave N2,N4-bis(3-hydroxyphenyl)-5-methyl-2,4-pyrimidinediamine. LCMS: ret. time: 16.76 min.; purity: 100%, MS (m/e): 309 (MH+).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08835430B2 |
| Quelldatensatz | uspto-grants-2014_09 |
| ORD ID | ord-8c6534cf8c2b4b498f754b21096ee7d9 |
| Quellennotiz | uspto-grants-2014_09 |