Methyl iodide → N-((S)-6-Bromo-1,2,3,4-tetrahydronaphthalen-2-yl)-N-methyl-5-cyclopropylmethoxy-pyridine-2-carboxamide

Beteiligte Stoffe

Reaktionsschritte

According to method G, (S)-6-bromo-1,2,3,4-tetrahydronaphthalen-2-ylamine was coupled with 5-hydroxypyridine-2-carboxylic acid and the product was then alkylated on the phenolic hydroxyl function with bromomethylcyclopropane according to method a Finally, the amide function was alkylated according to method B with methyl iodide. The product was thus obtained with the molecular weight of 415.33 (C21H23BrN2O2); MS (ESI): 415 (M+H+).

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