HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-Aminophenol → 4-(2-(N-isopropylcarbamoyl)-4-pyridyloxy)aniline
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-Aminophenol | HCID 403 | — |
| Edukt | Isopropylamine | HCID 6363 | — |
| Edukt | 4-chloropyridine-2-carbonyl Chloride | HCID 11095146 | — |
| Edukt | 4-Chloro-N-isopropyl-pyridine-2-carboxamide | HCID 22832083 | — |
| Produkt | 4-(2-(N-isopropylcarbamoyl)-4-pyridyloxy)aniline | HCID 23614560 | — |
Reaktionsschritte
Entry 66: 4-Chloropyridine-2-carbonyl chloride was reacted with isopropylamine according to Method A2, Step 3b. The resulting 4-chloro-N-isopropyl-2-pyridinecarboxamide was reacted with 4-aminophenol according to Method A2, Step 4 to give 4-(2-(N-isopropylcarbamoyl)-4-pyridyloxy)aniline. According to Method C1a, 4-chloro-3-(trifluoromethyl)phenyl isocyanate was reacted with 4-(2-(N-isopropylcarbamoyl)-4-pyridyloxy)aniline to afford the urea.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08841330B2 |
| Quelldatensatz | uspto-grants-2014_09 |
| ORD ID | ord-c539b59d73c647f095d385aa6e2369be |
| Quellennotiz | uspto-grants-2014_09 |