Dodecanoyl chloride → Dodecanoic acid, 2-(dimethylamino)-1-methylethyl ester

HRID 78384

Reaktionsgleichung

Reaktionsgleichung von HRID 78384
[C:1](Cl)(=[O:13])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12].C(N(CC)CC)C.[CH3:22][N:23]([CH2:25][CH:26]([OH:28])[CH3:27])[CH3:24]>C(Cl)(Cl)Cl>[C:1]([O:28][CH:26]([CH3:27])[CH2:25][N:23]([CH3:24])[CH3:22])(=[O:13])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12]

Komponenten

5

Edukt 3

HCID 8166Dodecanoyl chloride2×HCID 8471Triethylamine2×HCID 37511Dimepranol

Produkt 1

HCID 157516Dodecanoic acid, 2-(dimethylamino)-1-methylethyl ester

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6212ChloroformLösungsmittel2×

Versuchsvorschrift

The (N,N-disubstituted amino)-alkanol alkanoates are readily prepared by reacting the corresponding aminoalkinol with lauroyl chloride in the presence of triethylamine. A solvent such as chloroform is optional but preferred. For example, 1-(N,N-dimethylamino)-2-propanol can be reacted with lauroyl chloride in chloroform and in the presence of triethylamine to form 1-(N,N-dimethylamino)-2-propanol dodecanoate (DAIPD).

Quellen und Nachweise

ORD-Eintrag
ord-bf52ec518a5245d2b9e2bd2b666bbaa9
Quelldatensatz
uspto-grants-2014_09
Patentnummer
US08841345B2

Verknüpfte Notizen

Wird geladen…