Oxalyl chloride → 2,2,3,3-Tetramethylcyclopropane-1-carbonyl chloride

Beteiligte Stoffe

Reaktionsschritte

To a solution of 2,2,3,3-tetramethylcyclopropanecarboxylic acid (0.50 g, 3.5 mmol) in 18 mL of methylene chloride at 0° C. was added oxalyl chloride (0.61 mL, 7.0 mmol) and a catalytic amount of dimethylformamide (2 drops). The solution was stirred at ambient temperature for 1 hour, and then concentrated under reduced pressure to provide 0.56 g of the title compound.

Herkunft & Nachweise