Cyclopentylacetyl chloride → HCID 178495828, Verbindung

HRID 78413

Reaktionsgleichung

Reaktionsgleichung von HRID 78413
Br.[F:2][C:3]1[CH:16]=[CH:15][C:6]2[N:7]([CH2:11][CH2:12][O:13][CH3:14])[C:8](=[NH:10])[S:9][C:5]=2[CH:4]=1.[CH:17]1([CH2:22][C:23](Cl)=[O:24])[CH2:21][CH2:20][CH2:19][CH2:18]1>>[CH:17]1([CH2:22][C:23](/[N:10]=[C:8]2\[S:9][C:5]3[CH:4]=[C:3]([F:2])[CH:16]=[CH:15][C:6]=3[N:7]\2[CH2:11][CH2:12][O:13][CH3:14])=[O:24])[CH2:21][CH2:20][CH2:19][CH2:18]1

Komponenten

3

Edukt 2

HCID 3485182Cyclopentylacetyl chlorideHCID 686235486-Fluoro-3-(2-methoxyethyl)-3H-benzothiazol-2-ylideneamine hydrobromide

Produkt 1

HCID 178495828HCID 178495828, Verbindung

Versuchsvorschrift

The product from Example 113A and cyclopentylacetyl chloride were processed as described for example 11 to afford the title compound. 1H NMR (400 MHz, DMSO-d6) δ ppm 4.54 (d, J=5.76 Hz, 2H) 7.65 (t, J=8.14 Hz, 1H) 7.75 (dd, J=8.81, 2.71 Hz, 1H) 7.83 (dd, J=7.97, 1.53 Hz, 2H) 7.97 (dd, J=8.14, 1.36 Hz, 1H) 8.41 (d, J=3.05 Hz, 1H); MS (ESI+) m/z 337 (M+H)+; Anal. Calculated for C17H21FN2O2S: C, 60.69; H, 6.29; N, 8.33. Found: C, 60.67; H, 6.41; N, 8.25.

Quellen und Nachweise

ORD-Eintrag
ord-50646d728c214f4182c5b9507e333afd
Quelldatensatz
uspto-grants-2014_09
Patentnummer
US08841334B2

Verknüpfte Notizen

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