2-Bromoethyl methyl ether → 2-imino-3-(2-methoxyethyl)-6,6-dimethyl-2,3-dihydrofuro[3,4-d]thiazol-4(6H)-one hydrobromide

Reaktionsgleichung

[NH2:1][C:2]1[S:3][C:4]2[C:9]([CH3:11])([CH3:10])[O:8][C:7](=[O:12])[C:5]=2[N:6]=1.[CH3:13][O:14][CH2:15][CH2:16][Br:17]>>[BrH:17].[NH:1]=[C:2]1[N:6]([CH2:16][CH2:15][O:14][CH3:13])[C:5]2[C:7](=[O:12])[O:8][C:9]([CH3:10])([CH3:11])[C:4]=2[S:3]1

Komponenten

Edukt 2

HCID 809722-Bromoethyl methyl ether

HCID 875189862-Amino-6,6-dimethylfuro[3,4-d]thiazol-4(6h)-one

Produkt 1

HCID 686231172-imino-3-(2-methoxyethyl)-6,6-dimethyl-2,3-dihydrofuro[3,4-d]thiazol-4(6H)-one hydrobromide

Versuchsvorschrift

A mixture of Example 249B and commercially available 2-bromoethyl methyl ether (Aldrich) was processed at 120° C. using the method described in Example 12A to afford the title compound. MS (ESI+) m/z 243 (M+H)+

Aufarbeitung

customwas processed at 120° C.

Quellen und Nachweise

ORD-Eintrag: ord-a8e15ede7c2543369b68c82adcf8739d
Quelldatensatz: uspto-grants-2014_09
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US08841334B2

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